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Updated: Aug 9, 2026

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
Published on: November 30, 2022
[Drug safety of NSAIDs and COX-2 inhibitors]
Thomas Herdegen1, Joachim Fauler
1Institut für Pharmakologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel.
Abstract:
In this review the risk-benefit ratio of COX-2 inhibitors and NSAIDs is compared. In the discussion of the safety of these two groups different evaluation standards are used, which is not a basis of a rational pharmacotherapy.
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