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Updated: Aug 9, 2026

Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS
08:38

Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS

Published on: November 8, 2015

[Drug interactions of tacrolimus]

Melanie E Sumner1, Stefanie Albers, Klaus G Schmidt

  • 1Klinische Pharmazie und Pharmakotherapie, Heinrich-Heine-Universität Düsseldorf.

Medizinische Monatsschrift Fur Pharmazeuten
|April 25, 2006
PubMed

Allogeneic hematopoetic stem cell transplantations can be complicated by a graft-versus-host disease (GvHD), i.e., immunocompetent cells from the transplanted bone marrow act against solid organs of the recipient. A GvHD is treated with immunosuppressants. Consequently, further drugs are required, for example in order to prevent infections and result in in polymedication of those patients with a risk of drug interactions. In this case report, drug interactions between tacrolimus and concomitant therapy in a stem-cell-transplanted patient are discussed.

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