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Published on: June 30, 2020
The National Children's Study and the children of Wisconsin
Leonardo Trasande1, Christine E Cronk, Steven R Leuthner
1Center for Children's Health and the Environment, Mount Sinai School of Medicine, New York, NY 10029, USA. leo.trasande@mssm.edu
Insights
The National Children's Study will identify environmental risk factors for childhood chronic diseases like asthma and obesity. This large-scale study will track 100,000 children through age 21 to inform disease prevention strategies.
Area of Science:
- Pediatric Environmental Health
- Epidemiology
- Public Health
Background:
- Long-term epidemiologic studies have identified chronic illness risk factors.
- The Children's Health Act of 2000 authorized the National Children's Study.
- Previous studies provide a foundation for investigating environmental impacts on child health.
Purpose of the Study:
- To identify environmental risk factors for chronic diseases in children.
- To inform disease prevention strategies for pediatric populations.
- To train future researchers in pediatric environmental health.
Main Methods:
- Prospective, multi-year enrollment of 100,000 children nationwide.
- Follow-up of participants through age 21.
- Environmental assessments and biomarker analysis during pregnancy and childhood.
Main Results:
- The study aims to provide data on preventable risk factors.
- Expected insights into asthma, birth defects, neurobehavioral syndromes, and obesity.
- Will generate critical information for public health interventions.
Conclusions:
- The National Children's Study is a significant initiative for understanding environmental influences on child health.
- Findings will guide the prevention of major chronic diseases.
- The study will advance the field of pediatric environmental health research.
Abstract:
Prospective, multi-year epidemiologic studies such as the Framingham Heart Study and the Nurses' Health Study have proven highly effective in identifying risk factors for chronic illness and in guiding disease prevention. Now, in order to identify environmental risk factors for chronic disease in children, the US Congress authorized a National Children's Study as part of the Children's Health Act of 2000. Enrollment of a nationally representative cohort of 100,000 children will begin in 2008, with follow-up to continue through age 21. Environmental assessment and examination of biomarkers collected at specified intervals during pregnancy and childhood will be a major component of the Study. Recruitment at 105 sites across the United States is planned, and will begin at 7 Vanguard Centers in 2008, including Waukesha County, Wis. The National Children's Study will provide information on preventable risk factors for such chronic diseases as asthma, certain birth defects, neurobehavioral syndromes, and obesity. In addition, the National Children's Study will provide training in pediatric environmental health for the next generation of researchers and practitioners.
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