Related Experiment Video
Updated: Aug 9, 2026

06:26
Micro-Colony Forming Unit Assay for Efficacy Evaluation of Vaccines Against Tuberculosis
Published on: July 28, 2023
Improving immunization coverage through budgeted microplans and sub-national performance agreements: early experience
S C Soeung1, B M J Grundy, C K Ly
1National Immunisation Program, Ministry of Health, Phnom Penh, Cambodia.
Asia-Pacific Journal of Public Health
|April 25, 2006
Summary
Cambodia
Area of Science:
- Global Health
- Public Health Policy
- Immunization Programs
Background:
- Routine immunization rates in Cambodia have stagnated over the past five years.
- Despite successes in campaign-based initiatives like measles control, overall vaccination coverage requires improvement.
Purpose of the Study:
- To describe the Coverage Improvement Planning (CIP) process implemented by Cambodia's National Immunization Program.
- To identify barriers and outline strategies for enhancing routine immunization coverage.
Main Methods:
- The study details the implementation of the CIP process in Cambodia.
- It analyzes factors contributing to coverage improvements in pilot districts.
Main Results:
- Following CIP implementation in 2003, 8 out of 10 pilot districts saw increased immunization coverage.
- An average annual increase of 16% in DPT3 coverage was observed, indicating early effectiveness.
Conclusions:
- The CIP process, incorporating needs-based micro-planning, performance-based contracting, social mobilization, and strengthened monitoring, shows promise.
- Lessons learned from this pilot are crucial for scaling up national immunization efforts.
Related Concept Videos
Microorganisms in Medicine and Therapeutics
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
Vaccinations
Overview
Vaccine Production
Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...
