[Nosocomial infection by multidrug-resistant Pseudomonas Aeruginosa (MDRP) presumably spread a radiation technician]

Shin Nihonyanagi1, Yasuyosi Hirata, Tooru Akabosi

  • 1Department of Medical Laboratory, Kitasato University Hospital.

Insights

Multidrug-resistant Pseudomonas aeruginosa (MDRP) strains were identified in hospitalized patients. A radiation technician

Area of Science:

  • Clinical Microbiology
  • Infectious Diseases
  • Hospital Epidemiology

Background:

  • Multidrug-resistant Pseudomonas aeruginosa (MDRP) poses a significant threat in healthcare settings.
  • Identifying the transmission routes of MDRP is crucial for infection control.

Purpose of the Study:

  • To investigate the source and transmission of MDRP isolated from two patients in a hospital.
  • To determine if the isolated MDRP strains were genetically identical.

Main Methods:

  • Antimicrobial susceptibility testing and biochemical characterization.
  • Serotyping and Random Amplified Polymorphic DNA (RAPD) analysis for molecular epidemiology.
  • Review of patient clinical backgrounds and hospital procedures.

Main Results:

  • Two MDRP strains isolated from patients were identical by serotype and RAPD analysis.
  • The strains exhibited Class B (metallo)-beta-lactamase activity.
  • A single radiation technician performed X-rays on both patients shortly after each other.

Conclusions:

  • The MDRP strains were likely transmitted via contact infection.
  • The transmission was suspected to occur through a radiation technician who neglected hand hygiene.
  • This highlights the importance of strict adherence to infection control protocols in hospitals.

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