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Updated: Aug 9, 2026

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Published on: January 17, 2018
Cutaneous neuroendocrine adenoma: an uncommon neoplasm
M Mahalingam1, J F Kveaton, J Bhawan
1UMass Memorial Medical Center, Memorial Campus, Worcester, MA 01605, USA. mahalinm@ummhc.org
Background:
Cutaneous neuroendocrine neoplasms are typically malignant. Benign cutaneous neuroendocrine tumors are uncommon.
Methods:
We report the case of a 32-year-old female who presented with a granular mass in the right external auditory canal.
Results:
Microscopic examination of a shave biopsy revealed a poorly circumscribed neoplasm with glandular differentiation. While cytologic atypia and mitotic activity were not evident, pagetoid spread was observed. Immunohistochemistry was indicative of neuroendocrine origin.
Conclusions:
This case report of neuroendocrine adenoma indicates that this entity should be entertained in the repertoire of conditions affecting the external ear.
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