Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Calibration of acoustic transients.

Robert Burkard1

  • 1Center for Hearing and Deafness, 137 Cary Hall, University of Buffalo, Buffalo, NY 14214, USA. rfb@acsu.buffalo.edu

Brain Research
|April 25, 2006
PubMed
Summary

Standardizing auditory brainstem response calibration in mice is crucial. This review details appropriate stimulus parameters and calibration methods (peSPL, pSPL) for comparing hearing thresholds across studies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An absent WD domain in the autophagy protein ATG16L1 leads to auditory and vestibular dysfunction and otoconial deficits in mice.

International journal of audiology·2025
Same author

Offset auditory brainstem response (ABR) amplitude in bottlenose dolphins.

The Journal of the Acoustical Society of America·2020
Same author

Clinical Practice Guideline: Ménière's Disease.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2020
Same author

Clinical Practice Guideline: Ménière's Disease Executive Summary.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2020
Same author

Firefighter protective clothing and self contained breathing apparatus does not alter balance testing using a standard sensory organization test or motor control test in healthy, rested individuals.

Applied ergonomics·2019
Same author

The Effect of Recording Montage and Tone Burst Duration on Cervical and Ocular Vestibular Evoked Myogenic Potential Latency and Amplitude.

American journal of audiology·2019

Area of Science:

  • Neuroscience
  • Auditory Neuroscience
  • Animal Models

Background:

  • Auditory brainstem responses (ABRs) are essential for assessing hearing function.
  • Standardized methods for eliciting ABRs in mice are lacking, hindering cross-laboratory comparisons.
  • Accurate calibration of acoustic stimuli is critical for reliable ABR measurements.

Purpose of the Study:

  • To review appropriate stimulus parameters for eliciting ABRs in mice.
  • To discuss equipment specifications for acoustic transient calibration.
  • To present methods for calibrating acoustic transient levels, including peSPL and pSPL.

Main Methods:

  • Review of stimulus parameters: click duration and toneburst envelope.
  • Discussion of equipment specifications for acoustic calibration.
  • Presentation of calibration methods: peak equivalent sound pressure level (peSPL) and peak sound pressure level (pSPL).

Main Results:

  • Identified key stimulus parameters for mouse ABRs.
  • Outlined necessary equipment for acoustic calibration.
  • Described methods for measuring acoustic transient levels.

Conclusions:

  • Standardized acoustic calibration methods are needed for ABR threshold measurements in mice.
  • Adoption of standardized methods will improve the comparability of hearing thresholds across different laboratories and mouse strains.

Related Experiment Videos