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Craniofacial resection for sinunasal tumors.

M Granados-García1, M A Celis-López, J L Aguilar-Ponce

  • 1Department of Head and Neck Surgery, Instituto Nacional de Cancerología, México, Tlalpan. martingranadosmx@yahoo.com.mx

Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
|April 25, 2006
PubMed
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Craniofacial resection effectively treats advanced sinonasal tumors involving the cranial base. This retrospective analysis of 20 patients showed a 65% three-year overall survival, indicating its value despite complications.

Area of Science:

  • Oncology
  • Surgical Oncology
  • Head and Neck Surgery

Background:

  • Malignant sinonasal tumors are rare and often diagnosed at advanced stages in Mexico.
  • Early diagnosis is challenging, complicating treatment decisions for these diverse lesions.

Purpose of the Study:

  • To evaluate the outcomes of craniofacial resections for sinonasal tumors.
  • To assess the safety and efficacy of surgical management for advanced sinonasal malignancies.

Main Methods:

  • Retrospective analysis of 20 patients (11 male, 9 female) with sinonasal tumors.
  • Median age was 49 years; 11 patients had prior treatment.
  • Tumor extent varied, with some involving the orbit, dura, and brain.

Main Results:

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  • Overall complication rate was 50%, with major complications in 20% of patients.
  • Three-year overall survival was 65%, and disease-free survival was 50%.
  • Patients without prior treatment had a median survival of 28.3 months compared to 18.2 months for those with prior treatment.

Conclusions:

  • Craniofacial resection is a safe and valuable treatment for advanced sinonasal tumors invading the cranial base.
  • The procedure demonstrates significant survival benefits, particularly for patients without prior treatment.