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An unusual case of brain abscess by Gemella morbillorum
Maria Carla Liberto1, Giovanni Matera, Rossana Puccio
1Department of Medical Sciences, Institute of Microbiology, University of Catanzaro, Catanzaro, Italy. mliberto@unicz.it
Abstract:
A case of deep brain abscess by Gemella morbillorum is described. Due to high fever, lethargy, severe headache, and the risk of intraventricular rupture of the suppurative lesion, a CT-guided stereotactic aspiration of the abscess was successfully performed. The patient responded well to a 6-week course of meropenem, metronidazole, and fluconazole. Gemella spp. should not be considered as trivial commensals of the mucous membranes, but appear as emerging pathogens involved in endocarditis, septic shock, and necrotizing pneumonia, as well as in serious intracranial infections.
Insights
Gemella morbillorum can cause serious deep brain abscesses, requiring prompt CT-guided aspiration and a six-week antibiotic course. This case highlights Gemella spp. as emerging pathogens in severe infections, not just harmless commensals.
Area of Science:
- Neurology
- Infectious Diseases
- Microbiology
Background:
- Gemella morbillorum is a gram-positive coccus, part of the normal oral and genitourinary flora.
- While often considered commensal, Gemella species have been implicated in various infections, including endocarditis and bacteremia.
Observation:
- A patient presented with symptoms indicative of a deep brain abscess, including high fever, lethargy, and severe headache.
- Imaging revealed a suppurative lesion with a risk of intraventricular rupture.
Findings:
- A CT-guided stereotactic aspiration successfully drained the deep brain abscess.
- The patient received a 6-week treatment regimen comprising meropenem, metronidazole, and fluconazole, with a positive clinical response.
Implications:
- This case underscores Gemella morbillorum as a potential cause of severe intracranial infections.
- The findings suggest Gemella spp. are emerging pathogens that warrant consideration in serious infections beyond their typical commensal role.
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