[Changes in a semen analysis related to spontaneous pregnancy in patients with infertility history]

To describe changes in a semen analysis before getting a spontaneous pregnancy.

In an observational, descriptive, longitudinal and retrospective study a semen analysis of the first evaluation of 96 patients was compared with the exam accomplished before getting a spontaneous pregnancy. A descriptive analysis of the semen exam was performed and the results of both exams were compared by means of at Student test with statistical significance for p < 0.05.

In the first analysis, the volume, density, mobility, normal morphology, total number of mobile cells and total number of mobile cells with normal morphology (TNMCNM) were 2.45 +/- 1.39 mL, 79 +/- 43 million/mL, 40 +/- 21%, 27 +/- 14%, 84 +/- 84 million and 23 +/- 29 million, respectively, and in the final analysis were 2.6 +/- 1.26 mL, 79 +/- 42 million/mL, 43 +/- 21%, 28 +/- 14%, 97 +/- 98 million and 28 +/- 33 million, respectively. None of them were different. In four patients with low testosterone and a LH/FS > or = 1 ratio, volume increased from 1 +/- 0.31 to 1.65 +/- 0.17 mL and normal morphology from 22 +/- 7 to 31 +/- 5. Both variables were different. In six patients with high prolactine and low testosterone or low FSH, density increased from 56 +/- 21 to 114 +/- 18 million/mL and TNMCNM from 14 +/- 12 to 46 +/- 32 million. Both variables were different.

Only those patients with low testosterone and a LH/FSH > or = 1 rate had an increase of semen volume and normal morphology. Those with high prolactine-low testosterone or high prolactine-low FSH had an increase of the total mobile cells and the total mobile cells with normal morphology. There were not changes in any semen variable of the other patients.