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Related Experiment Videos

Slow-frequency rTMS reduces fibromyalgia pain.

Shirlene M Sampson1, Jeffrey D Rome, Teresa A Rummans

  • 1Department of Psychiatry and Psychology, W11A, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA. sampson.shirlene@mayo.edu

Pain Medicine (Malden, Mass.)
|April 26, 2006
PubMed
Summary

Repetitive transcranial magnetic stimulation (rTMS) significantly reduced pain in women with fibromyalgia. This treatment shows promise for managing chronic pain conditions like fibromyalgia.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Pain Management

Background:

  • Fibromyalgia (FM) is recognized as a central pain disorder.
  • Antidepressant therapies, including electroconvulsive therapy, offer symptomatic relief for FM and other chronic pain conditions.
  • Repetitive transcranial magnetic stimulation (rTMS) is an emerging antidepressant treatment with potential applications in pain management.

Purpose of the Study:

  • To investigate the efficacy of repetitive transcranial magnetic stimulation (rTMS) as a treatment for fibromyalgia (FM) pain.
  • To explore the potential of rTMS in managing centrally mediated pain disorders.

Main Methods:

  • A cohort of four women diagnosed with depression, FM, and borderline personality disorder participated.
  • 1-Hz rTMS was applied to the right dorsolateral prefrontal cortex in these participants.

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  • Pain intensity was self-assessed using an 11-point Likert scale before and after treatment.

    • Main Results:

    • Pretreatment average pain score was 8.2, significantly decreasing to 1.5 post-rTMS (P < 0.009).
    • All participants experienced a reduction in pain, with two achieving complete pain resolution.
    • Only one subject demonstrated an antidepressant response, suggesting pain relief may be independent of mood improvement in this sample.

    Conclusions:

    • Preliminary results indicate that rTMS may be a viable therapeutic option for alleviating fibromyalgia pain.
    • Further research is warranted to confirm the role of rTMS in treating FM and other chronic pain conditions.