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Updated: Aug 9, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
Primary Aspergillus and Fusarium keratitis in a Holstein cow
Colleen R Elligott1, David A Wilkie, Vanessa J Kuonen
1Florida Veterinary Specialists, 3000 Busch Lake Blvd., Tampa, Florida 33614, USA. dogdoc2b@hotmail.com
Abstract:
A 5-year-old female Holstein cow was examined for ocular discharge, periorbital swelling, an area of full-thickness corneal cellular infiltrate, fibrin, hypopyon, diffuse corneal edema, and miosis. The patient was diagnosed with a corneal stromal abscess and secondary anterior uveitis. Histopathology, mycotic culture, and polymerase chain reaction positive for Aspergillus and Fusarium DNA confirmed the presence of fungal infection. Response to therapy was adequate, and follow-up with the patient 1 year after diagnosis revealed a focal area of corneal fibrosis.
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