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Updated: Aug 9, 2026
Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection
Published on: April 12, 2024
Fibrous hamartoma of infancy: an Italian multi-institutional experience
Elena Carretto1, Patrizia Dall'Igna, Rita Alaggio
1Division of Paediatric Surgery, Department of Paediatrics, University of Padua, Padua, Italy.
Background:
Fibrous hamartoma (FH) of infancy is a benign mesenchymal tumor, occurring as a superficial mass. Complete excision is curative.
Objective And Methods:
The clinical features and treatment results of 18 children with FH are described.
Results:
Local excision was the most common procedure. Surgery was radical in 10 patients, with microscopic residual disease in 6; all of them are alive with no evidence of disease 2 to 49 months after diagnosis. One patient, treated with a local reexcision for macroscopic residual disease (and chemotherapy for a synchronous desmoid fibromatosis) is well 83 months after diagnosis; the last patient, with a lesion of the labia majora, only underwent biopsy and is doing well, awaiting plastic surgery.
Limitations:
The results did not reach statistical significance due to difficulties in collecting cases.
Conclusions:
FH should be treated by complete excision; in our experience a nonradical excision was also able to achieve the cure. An aggressive approach should be avoided, as the overall prognosis is excellent.
