Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Superficial siderosis.

N Kumar1, A A Cohen-Gadol, R A Wright

  • 1Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA. kumar.neeraj@mayo.edu

Neurology
|April 26, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

40-Year Incidence of Early-Onset Parkinson's Disease in Southeast Minnesota.

Journal of Parkinson's disease·2023
Same author

A system for detecting high impact-low frequency mutations in primary tumors and metastases.

Oncogene·2017
Same author

Utility of neurological smears for intrasurgical brain cancer diagnostics and tumour cell percentage by DESI-MS.

The Analyst·2017
Same author

The clinical spectrum and natural history of pure akinesia with gait freezing.

Journal of neurology·2016
Same author

Genome-wide gene-environment interaction analysis of pesticide exposure and risk of Parkinson's disease.

Parkinsonism & related disorders·2016
Same author

Highly specific radiographic marker predates clinical diagnosis in progressive supranuclear palsy.

Parkinsonism & related disorders·2016
Same journal

Factors Associated With Disability Improvement and Worsening Independent of Attacks in Patients With AQP4-IgG+ NMOSD and MOGAD: A Multicenter Cohort Study.

Neurology·2026
Same journal

Cost-Effectiveness of Intracranial Aneurysm Screening: A Systematic Review.

Neurology·2026
Same journal

Rare Eating Epilepsy: Co-Occurrence of Focal Cortical Dysplasia and Gray Matter Heterotopia.

Neurology·2026
Same journal

Spatiotemporal Associations Between Cortical Microinfarcts and Cortical Superficial Siderosis in Cerebral Amyloid Angiopathy.

Neurology·2026
Same journal

Blood-Brain Barrier Disruption Before Interhospital Transfer for Thrombectomy and Clinical Outcome.

Neurology·2026
Same journal

At Death's Door: Cytosolic Dopamine in Patients With Parkinson Disease.

Neurology·2026
See all related articles

Superficial siderosis (SS) often lacks a clear bleeding history, with trauma being a common cause. MRI reveals characteristic findings and spinal fluid collections, guiding potential surgical repair of dural defects.

Area of Science:

  • Neurology
  • Neuroradiology
  • Neurosurgery

Background:

  • Superficial siderosis (SS) involves hemosiderin deposition in the CNS due to chronic subarachnoid bleeding.
  • The origin of bleeding in SS is frequently unidentified despite investigations.

Purpose of the Study:

  • To analyze clinical and imaging features in 30 superficial siderosis patients.
  • To investigate potential causes of subarachnoid bleeding in SS.

Main Methods:

  • Retrospective review of medical records for 30 patients with SS.
  • Assessment of clinical data and MRI findings.

Main Results:

  • Gait ataxia and hearing impairment were common symptoms.
  • Prior trauma was identified in 15 patients as a potential cause.

Related Experiment Videos

  • MRI showed characteristic SS findings and spinal fluid collections in 14 patients.

    • Conclusions:

    • History of subarachnoid hemorrhage is often absent; trauma is a frequent precursor.
    • Spinal fluid collections on MRI are common and linked to SS.
    • Surgical repair of dural defects may be considered for bleeding sources.