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Updated: Aug 9, 2026
09:01
Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation
Published on: October 15, 2021
Long-term mortality after intracerebral hemorrhage
M L Flaherty1, M Haverbusch, P Sekar
1Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH 45267-0525, USA. matthew.flaherty@uc.edu
Neurology
|April 26, 2006
Summary
Long-term mortality following intracerebral hemorrhage (ICH) remained unchanged between two large population cohorts separated by over a decade. Surgical intervention for ICH decreased, while anticoagulant-related cases increased.
Area of Science:
- Neurology
- Epidemiology
- Public Health
Background:
- Intracerebral hemorrhage (ICH) is a critical subtype of stroke with high mortality.
- Understanding long-term survival trends is essential for evaluating healthcare interventions and outcomes.
- Previous studies have indicated potential improvements in stroke care, but data on ICH specifically are limited.
Purpose of the Study:
- To assess and compare long-term mortality rates in patients with intracerebral hemorrhage (ICH) across two distinct population-based cohorts.
- To identify changes in patient demographics, treatment approaches, and outcomes between the two study periods.
Main Methods:
- Two large population-based cohorts of non-traumatic intracerebral hemorrhage (ICH) patients were analyzed, with the first cohort from 1988 and the second from 1998-2003.
- Mortality data were collected and analyzed using actuarial methods.
- Statistical comparison between the cohorts was performed using a log-rank test.
Main Results:
- Cohort 1 included 183 ICH patients; Cohort 2 included 1,041 ICH patients.
- Patients in Cohort 1 were more likely to be white and undergo surgery for ICH compared to Cohort 2.
- Mortality at 7 days, 1 year, and 10 years for Cohort 1 was 31%, 59%, and 82%, respectively. For Cohort 2, 7-day and 1-year mortality were 34% and 53%. No significant difference in mortality rates was observed between the cohorts (p = 0.259).
Conclusions:
- Long-term mortality following intracerebral hemorrhage (ICH) did not show significant improvement between the two study periods.
- There was a decrease in the frequency of surgical operations for ICH.
- An increase in the incidence of anticoagulant-associated ICH was observed.
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