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Updated: Aug 9, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Summary
A novel skincare regimen, including a surfactant-free cleanser and moisturizer with amino acids, vitamins, antioxidants, and methylsulfonylmethane, effectively treated severe X-linked ichthyosis. This over-the-counter approach resolved skin scaling, discomfort, and itching in a patient unresponsive to other treatments.
Area of Science:
- Dermatology
- Genetics
Background:
- Ichthyoses are rare, genetic, incurable skin diseases affecting over 1 million Americans.
- These conditions cause dry, thickened, scaling skin, leading to disfigurement and significant physical, social, and emotional distress.
- Current topical treatments primarily focus on symptom management.
Observation:
- A 44-year-old male patient with severe X-linked ichthyosis showed no improvement with various topical and systemic therapies.
- A new daily regimen included a surfactant-free cleanser and a moisturizer with amino acids, vitamins, antioxidants, and methylsulfonylmethane.
Findings:
- After 4 weeks, the test area on the patient's arm showed clear skin with reduced discomfort and itching.
- Application to other affected areas resulted in no adverse reactions and continued skin improvement.
Implications:
- This over-the-counter skincare regimen demonstrates potential as a viable treatment option for X-linked ichthyosis.
- The findings suggest this approach may benefit other patients with similarly compromised skin conditions.
- Patient satisfaction and symptom resolution highlight the efficacy of this management strategy.
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