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Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module
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Vitamin B6 suppresses growth of the feline mammary tumor cell line FRM

Dai Shimada1, Ayumi Fukuda, Hiroaki Kanouchi

  • 1Department of Veterinary Physiology, Faculty of Agriculture, Kagoshima University, Kagoshima, Japan.

Bioscience, Biotechnology, and Biochemistry
|April 26, 2006
PubMed

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Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...