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Updated: Aug 6, 2026

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
Severe acute pancreatitis and pregnancy
K W Robertson1, I S Stewart, C W Imrie
1Lister Department of Surgery, Glasgow Royal Infirmary, Glasgow, UK. kwrobertson@doctors.org.uk
Pregnancy-associated pancreatitis can be severe, even in young women, posing a survival threat. Gallstones are a common cause, necessitating awareness and timely intervention for severe acute pancreatitis during pregnancy.
Area of Science:
- Gastroenterology
- Obstetrics & Gynecology
Background:
- Pregnancy-associated pancreatitis typically has a low maternal mortality rate.
- Severe acute pancreatitis during pregnancy is rare but can be life-threatening.
Observation:
- This study describes 4 young women (ages 17-24) with severe acute pancreatitis during pregnancy.
- All cases were associated with gallstones and required intensive management.
- Hospital stays ranged from 37 to 90 days, with significant complications.
Findings:
- One patient needed pancreatic necrosectomy for infected necrosis.
- Another underwent percutaneous management for a pancreatic abscess.
- Two patients were treated for pancreatic pseudocysts with cystogastrostomy.
- All patients had early endoscopic sphincterotomy and later cholecystectomy.
Implications:
- Pregnancy-associated acute pancreatitis can present severely, even in young patients.
- Gallstones are a significant etiological factor in severe cases.
- Early recognition and intervention are crucial for improving outcomes in these high-risk pregnancies.
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