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In Vivo Gene Transfer to the Rabbit Common Carotid Artery Endothelium
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Development of a novel perfusion technique to allow targeted delivery of gene therapy--the V-Focus system

Arthur C Preovolos1, Mark T Mennen, Adam Bilney

  • 1Baker Heart Research Institute, Melbourne, Australia.

The Journal of Extra-Corporeal Technology
|April 28, 2006
PubMed
Abstract

No abstract available in PubMed .

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Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...

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