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An immunoprecipitation assay for the detection of onconeural antibodies
1Department of Neurology, Haukeland University Hospital; Department of Clinical Medicine, University of Bergen, Norway. sissel.monstad@helse_bergen.no
Introduction:
Onconeural antibodies are found in some patients with cancer, and are associated with paraneoplastic neurological syndromes.
Method:
A multi-well adapted fluid-phase immunoassay using radiolabelled recombinant onconeural proteins for the detection of onconeural antibodies is described.
Result And Conclusion:
This immunoprecipitation technique is more sensitive in detecting onconeural antibodies than immunohistochemistry and immune blots.
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