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Published on: April 25, 2014

Depression assessed over 1-year survival in patients with myocardial infarction

C Sørensen1, A Brandes, O Hendricks

  • 1The Medical Research Unit, Ringkøbing County, Ringkøbing, Denmark. chs@dadlnet.dk

Acta Psychiatrica Scandinavica
|April 28, 2006
PubMed

Insights

Nearly 10% of myocardial infarction (MI) patients experience depression at discharge. While not an independent predictor, depression severity correlated with increased 1-year mortality, particularly in non-Q-wave MI cases.

Area of Science:

  • Cardiology
  • Psychiatry
  • Public Health

Background:

  • Myocardial infarction (MI) is a leading cause of mortality worldwide.
  • Depression is a common comorbidity following cardiac events.
  • The impact of depression on post-MI outcomes requires further investigation.

Purpose of the Study:

  • To determine the prevalence of depression in patients post-myocardial infarction (MI).
  • To assess the association between depression and 1-year mortality in MI patients.

Main Methods:

  • A cohort of 763 MI patients completed the Major Depression Inventory at discharge.
  • Patient data were collected from hospital records and national registries for 1-year follow-up.
  • Mortality and re-admission rates were tracked.

Main Results:

  • 9.6% of MI patients met diagnostic criteria for depression at discharge.
  • Depression was not an independent predictor of mortality.
  • A significant trend showed increased mortality with greater depression severity (P=0.028).
  • All mortality in depressed patients occurred in those with non-Q-wave MI.

Conclusions:

  • Approximately 10% of myocardial infarction patients are diagnosed with depression upon hospital discharge.
  • Increased depression severity is linked to a higher risk of mortality within one year post-MI.
  • Mortality among depressed MI patients was exclusively observed in those with non-Q-wave infarction, suggesting a need for targeted research in this subgroup.
Abstract

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