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Inhalants: not to be taken lightly anymore
1Prevention Research Center, Pennsylvania State University, State College, Pennsylvania 16801, USA. tar13@psu.edu
Current Opinion in Psychiatry
|April 28, 2006
Summary
Inhalant abuse causes significant medical, psychiatric, and psychological damage, including addiction and impaired cognition. Greater attention is needed for prevention and treatment programs for inhalant use disorder.
Area of Science:
- Neuroscience
- Psychiatry
- Public Health
Background:
- Inhalant abuse and dependence are often overlooked public health issues.
- Recent advances are improving our understanding of inhalant use consequences, pharmacology, and etiology.
Purpose of the Study:
- To review recent findings on inhalant use.
- To explore potential preventive and management strategies for inhalant abuse and dependence.
Main Methods:
- Review of recent scientific literature on inhalant use.
- Analysis of animal models for understanding reinforcement mechanisms.
- Discussion of diagnostic assays for inhalant detection.
Main Results:
- Animal models reveal GABA and dopamine pathways are key in inhalant reinforcement, tolerance, and dependence.
- Inhalant use is linked to severe medical issues, addiction to other substances, depression, suicide, and cognitive deficits.
- Accurate diagnostic assays for inhalants are becoming more available.
Conclusions:
- Inhalant use leads to extensive medical, psychiatric, and psychological harm.
- There is a critical need for developing prevention and treatment programs for inhalant abuse and dependence, which are currently lacking.
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