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Outcome from mild traumatic brain injury.

Grant L Iverson1

  • 1Department of Psychiatry, University of British Columbia, Neuropsychiatry Program, Riverview Hospital, Vancouver, British Columbia, Canada. giverson@interchange.ubc.ca

Current Opinion in Psychiatry
|April 28, 2006
PubMed
Summary

Mild traumatic brain injury (MTBI) outcomes are generally predictable, with most athletes recovering within two weeks. However, recovery can be complicated by various health and life factors in trauma patients.

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Area of Science:

  • Neuroscience
  • Neurology
  • Sports Medicine

Background:

  • Mild traumatic brain injury (MTBI) literature is vast, complex, and often controversial.
  • Recent research integrates pathophysiology, neuropsychological outcomes, and persistent postconcussion syndrome.
  • Athletes represent a significant focus for prospective MTBI research.

Purpose of the Study:

  • To review and integrate recent literature on mild traumatic brain injury outcomes.
  • To synthesize information on MTBI pathophysiology and neuropsychological sequelae.
  • To examine the persistent postconcussion syndrome in the context of current research.

Main Methods:

  • Literature review and integration of recent studies.
  • Analysis of pathophysiology, neuropsychological outcomes, and postconcussion syndrome.

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  • Focus on prospective research, particularly in athletic populations.

    • Main Results:

    • MTBI literature is extensive, complex, and methodologically varied.
    • Numerous studies on pathophysiology, neuropsychological outcomes, and postconcussion syndrome were published.
    • Athletic populations show promising prospective research findings.

    Conclusions:

    • Cognitive and neurobehavioral effects of MTBI are typically self-limiting and predictable.
    • MTBI involves a neurometabolic cascade with cellular recovery as the norm.
    • Athletes generally recover within 2-14 days, while trauma patients may face longer, complicated recovery.