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Updated: Aug 9, 2026

Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography
Published on: April 4, 2012
[Assessment of image display of contrast enhanced T1W images with fat suppression]
Isao Miyazaki1, Keiko Ishizaki, Kuninori Kobayashi
1Department of Radiology, Kyourin University Hospital.
Unlabelled:
The effects of imaging conditions and measures for their improvement were examined with regard to recognition of the effects of contrast on images when T1-weighted imaging with selective fat suppression was applied.
Method:
Luminance at the target region was examined before and after contrast imaging using phantoms assuming pre- and post-imaging conditions. A clinical examination was performed on tumors revealed by breast examination, including those surrounded by mammary gland and by fat tissue.
Results:
When fat suppression was used and imaging contrast was enhanced, the luminance level of fat tumors with the same structure as the prepared phantoms appeared to be high both before and after contrast imaging, and the effects of contrast were not distinguishable. This observation is attributable to the fact that the imaging conditions before and after contrast imaging were substantially different. To make a comparison between pre- and post-contrast images, it is considered necessary to perform imaging with fixed receiver gain and to apply the same imaging method for pre- and post-contrast images by adjusting post-contrast imaging conditions to those of pre-contrast imaging.

