Related Experiment Videos
International comparative study of childhood malignancy comparative study of pediatric malignancy between Kurume and
A Shakoor1, T Murakami, F Yamashita
1Department of Pediatric Pathology, National Institute of Child Health, JPMC, Karachi.
Insights
Pediatric cancer patterns differ significantly between developed and developing nations. Factors like environment, education, and socioeconomic status profoundly impact pediatric cancer development, alongside genetics.
Area of Science:
- Oncology
- Epidemiology
- Environmental Health
Background:
- Pediatric cancer incidence and etiology vary globally.
- Developed vs. developing nations present distinct challenges in pediatric oncology.
Purpose of the Study:
- Compare pediatric malignancy in Kurume, Japan, and Karachi, Pakistan.
- Identify differences in developed vs. developing countries influencing pediatric cancer.
- Investigate etio-pathogenesis factors of childhood cancer.
Main Methods:
- Retrospective study of pediatric cancers (1988-1990).
- Comparative analysis of population, socioeconomic, educational, and environmental factors.
- Utilized international data for reference.
Main Results:
- Karachi: 10 million population, poor socioeconomic status, 25% educated beyond middle school, severe pollution.
- Kurume: 0.5 million population, good socioeconomic status, 100% educated to high school, clean environment.
- Significant disparities in environmental, educational, and socioeconomic conditions observed.
Conclusions:
- Genetic predisposition is key in pediatric cancer.
- Environmental, educational, and socioeconomic factors significantly influence pediatric cancer patterns.
- These societal factors play a crucial role in pediatric carcinogenesis trends.
Unlabelled:
A study was undertaken to compare Pediatric Malignancy at Kurume (Japan) and Karachi (Pakistan) with reference to international data collected over the years, in order to identify essential differences between developed and developing conditions and factors influencing the etio-pathogenesis of pediatric cancer. The study was retrospective encompassing all types of cancer in children over a period of three years i-e 1988-1990. Essential factors related to present study were: 1.
Population:
The population of Karachi is about 10 million while that of Kurume is only half a million. 2. Socio-economic conditions: The average socio-economic condition of people in Karachi is poor while in Kurume it appears to be good. 3. Educational status: Only 25% people in Karachi are educated beyond middle class while Kurume reveals a 100% education up to high school level. 4. Environmental conditions: The environmental conditions of Kurume and surrounding areas are very clean and free from pollution, sewage problems and traffic hazards. Karachi and its surroundings on the other hand pose very serious air and water industries! It was concluded that whereas genetic predisposition predominates, the environmental conditions, educational and socio-economic status of a society immensely influence the pattern and trends of pediatric carcinogenesis.