Comments on "fundamental limits of reconstruction-based superresolution algorithms under local translation"

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Whole-cell Super-Resolution Imaging via DNA-PAINT on a Spinning Disk Confocal with Optical Photon Reassignment
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Whole-cell Super-Resolution Imaging via DNA-PAINT on a Spinning Disk Confocal with Optical Photon Reassignment

Published on: January 6, 2026

Liwei Wang1, Jufu Feng

  • 1Center for Information Sciences School of Electronics Engineering and Computer Sciences, Peking University, Beijing, China. wanglw@cis.pku.edu.cn

IEEE Transactions on Pattern Analysis and Machine Intelligence
|April 28, 2006
PubMed

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Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been developed.