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Cardiac pumping capability in patients with peripheral vascular disease
L D Hodges1, G R H Sandercock, S K Das
1Research Centre for Health Studies, BCUC, Gorelands Lane, Buckinghamshire, UK. lhodge01@bcuc.ac.uk
Clinical Physiology and Functional Imaging
|April 28, 2006
Summary
Patients with peripheral vascular disease (PVD) have reduced cardiovascular function. Exercise therapy can improve their cardiovascular capacity and walking ability.
Area of Science:
- Cardiovascular Physiology
- Exercise Science
- Vascular Medicine
Background:
- Peripheral vascular disease (PVD) involves lower extremity arterial blockages, leading to reduced functional capacity and exercise tolerance.
- Limited data exist on the cardiovascular response to maximal exercise in PVD patients.
- This study investigated key cardiovascular variables during maximal exercise in individuals with PVD.
Purpose of the Study:
- To evaluate the cardiovascular response to maximal exercise in patients diagnosed with peripheral vascular disease.
- To quantify parameters such as maximal oxygen consumption and cardiac output in this population.
Main Methods:
- Fifty PVD patients underwent incremental exercise testing to maximal claudication pain.
- Maximal oxygen consumption (VO2) was measured via breath-by-breath analysis.
- Cardiac output (QT) and peak cardiac power output (CPOpeak) were assessed post-rest using non-invasive rebreathing.
Main Results:
- Patients exhibited a mean VO2 of 13.85 ml kg min(-1) and maximal walk time of 357 seconds.
- Peak mean arterial pressure reached 127 mmHg.
- Average cardiac output was 9.8 L min(-1) with a CPOpeak of 2.86 W.
Conclusions:
- Peripheral vascular disease patients show diminished cardiovascular capacity during maximal exertion.
- Implementing exercise therapy is recommended to enhance cardiovascular status and improve functional mobility in PVD patients.
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