Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Assessing HIV resistance in developing countries: Brazil as a case study.

Maya L Petersen1, Marie-Claude Boily, Francisco I Bastos

  • 1Division of Epidemiology, University of California, School of Public Health, Berkeley, California, USA. mayaliv@gmail.com

Revista Panamericana De Salud Publica = Pan American Journal of Public Health
|April 28, 2006
PubMed
Summary

Expanded access to antiretroviral therapy (ART) may increase resistant HIV transmission. Brazil

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cost-Effectiveness Analyses for Sequential Multiple Assignment Randomized Trials.

Statistics in medicine·2026
Same author

Emergence of synthetic drugs in South America: insights from Brazil, Chile, and Colombia.

Harm reduction journal·2026
Same author

An approach to nonparametric inference on the causal dose-response function.

Journal of causal inference·2026
Same author

A megastudy of behavioral interventions to promote frequent HIV testing among adults at high risk of HIV infection in Kenya and Uganda: study protocol for a randomized controlled trial.

Trials·2026
Same author

Looking through the cracks: vulnerabilities and deprivation in the Brazilian open drug scenes.

Social science & medicine (1982)·2026
Same author

Sanctioning the supply chain: Analyzing US executive orders on tariffs as a tool against the fentanyl crisis.

Global public health·2026

Area of Science:

  • Public Health
  • Infectious Diseases
  • Virology

Background:

  • Expanded access to antiretroviral therapy (ART) raises concerns about increased transmission of drug-resistant HIV.
  • Resource limitations and healthcare infrastructure challenges may influence the spread of resistant HIV strains.

Purpose of the Study:

  • To review the impact of healthcare infrastructure on transmitted HIV drug resistance.
  • To examine HIV resistance data from Brazil as a case study.
  • To introduce a framework for identifying determinants of transmitted resistance.

Main Methods:

  • Literature review on resource limitations and HIV resistance.
  • Development of a biological and clinical framework for transmitted resistance.
  • Analysis of HIV resistance data from Brazil.

Related Experiment Videos

Main Results:

  • Brazil's experience shows ART can be delivered in resource-limited settings without widespread resistant HIV transmission.
  • The developed framework identified key determinants of transmitted resistance.
  • Data analysis supported the framework's application to the Brazilian context.

Conclusions:

  • Resource-limited settings can implement ART without necessarily leading to widespread resistant HIV transmission.
  • The Brazilian case study demonstrates successful ART delivery despite infrastructure challenges.
  • Further research is needed to generalize findings to diverse global settings, but widespread resistance is not a foregone conclusion.