Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optimizing localization accuracy in head and neck, and brain radiotherapy.

M McJury1, K Dyker, R Nakielny

  • 1Department of Radiotherapy Physics, Weston Park Hospital, Whitham Road, Sheffield, UK.

The British Journal of Radiology
|April 28, 2006
PubMed
Summary

Radiologist input significantly impacts radiotherapy planning target volumes (PTVs), especially for head and neck cases. Contrast-enhanced CT scans showed minimal changes for oncologists but significant differences when a radiologist contoured the data.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Using helium-oxygen to improve regional deposition of inhaled particles: mechanical principles.

Journal of aerosol medicine and pulmonary drug delivery·2014
Same author

Search for top squarks in R-parity-violating supersymmetry using three or more leptons and b-tagged jets.

Physical review letters·2013
Same author

Searches for new physics using the tt¯ invariant mass distribution in pp collisions at √s=8 TeV.

Physical review letters·2013
Same author

Direct measurement of the total decay width of the top quark.

Physical review letters·2013
Same author

Measurement of the differential cross section dσ/d(cosθ(t)) for Top-Quark Pair Production in pp Collisions at sqrt[s] = 1.96 TeV.

Physical review letters·2013
Same author

Inclusive search for supersymmetry using razor variables in pp collisions at √s=7 TeV.

Physical review letters·2013

Area of Science:

  • Medical Imaging
  • Radiation Oncology
  • Radiology

Background:

  • Accurate patient localization is crucial for effective radiotherapy.
  • Contrast-enhanced CT (CECT) may improve soft tissue visualization for treatment planning.
  • The role of radiologist input in contouring for radiotherapy planning requires further investigation.

Purpose of the Study:

  • To evaluate the impact of contrast-enhanced CT (CECT) scans and radiologist input on radiotherapy localization.
  • To compare contouring differences between oncologists and radiologists using CECT data.
  • To assess the effect on planning target volumes (PTVs) and treatment accuracy.

Main Methods:

  • Retrospective analysis of 25 head and neck/brain patient CT scans (pre- and post-contrast).

Related Experiment Videos

  • Radiotherapy plans were initially created on unenhanced CT scans.
  • Scans were re-contoured by oncologists and a radiologist; differences in volume, position, and coverage were analyzed.
  • Main Results:

    • Oncologist contouring on CECT showed minimal changes in gross tumor volumes (GTVs) and PTVs for brain cases.
    • Head and neck cases showed larger volume changes with oncologist contouring on CECT.
    • Radiologist contouring on CECT resulted in statistically significant differences in PTV volume (p < 0.05) and significant differences compared to oncologist-generated GTVs (p < 0.01).
    • Geographic shifts were generally within departmental tolerances.

    Conclusions:

    • Contrast-enhanced CT data has a limited effect on PTVs contoured by oncologists.
    • Radiologist input significantly alters PTVs, highlighting the importance of their expertise in radiotherapy planning.
    • Significant differences arise when comparing PTVs based on oncologist versus radiologist-generated GTVs.