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Brachial artery thrombosis in infants: an algorithm for limb salvage
Christopher J Coombs1, Phillip W Richardson, Guy J Dowling
1Department of Plastic and Maxillofacial Surgery, Royal Children's Hospital, Melbourne, Australia. chris@southernplasticsurgery.com.au
Plastic and Reconstructive Surgery
|April 28, 2006
Summary
Iatrogenic arterial occlusion in infants, often from vascular access, can lead to limb loss. A new management algorithm successfully treated 11 infants, preventing limb loss and guiding therapy with early recognition.
Area of Science:
- Pediatric surgery
- Vascular surgery
- Neonatology
Background:
- Iatrogenic arterial occlusion in infants, typically from arterial vascular access, can cause severe complications like gangrene and limb loss.
- Long-term growth disturbances may occur even if limb loss is avoided.
- Limited data exists for managing arterial occlusion in premature or sick infants.
Purpose of the Study:
- To present an algorithm for managing iatrogenic arterial occlusion in infants.
- To share experiences from the Royal Children's Hospital, Melbourne.
Main Methods:
- Retrospective review of 11 infant cases (1995-2003) with arterial vascular access-associated thrombosis.
- Development and application of a management algorithm.
Main Results:
- The algorithm successfully treated 11 limbs in 11 patients, preventing limb loss.
- Five patients required surgical intervention.
Conclusions:
- A multidisciplinary approach involving plastic surgeons and hematologists is recommended.
- A consensus algorithm for heparin, thrombolysis, and surgical interventions provides a useful therapeutic framework.
- Early recognition of the at-risk limb is crucial for successful outcomes.
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