Twin gestation pregnancies: genetic counseling and testing experience
Kathryn F Peters1, Brian M Saltsman, Stephen A Petrill
1Center for Developmental and Health Genetics, Department of Biobehavioral Health, Pennsylvania State University, University Park 16802, USA. kfp1@psu.edu
Journal of Genetic Counseling
|April 28, 2006
Summary
Few parents in multiple gestation pregnancies utilize genetic counseling services, despite potential benefits. Many who do meet with a genetic counselor still decline prenatal genetic testing.
Area of Science:
- Perinatal medicine
- Genetics
- Reproductive health
Background:
- Multiple gestation pregnancies present unique genetic risks.
- Prenatal genetic counseling and testing are crucial for informed decision-making.
Purpose of the Study:
- To evaluate the uptake of prenatal genetic counseling and testing in multiple gestation pregnancies.
- To identify factors associated with the utilization of these services.
Main Methods:
- Retrospective analysis of 343 multiple gestation pregnancies.
- Self-reported data on genetic counseling encounters and prenatal testing choices.
- Statistical analysis to identify correlations.
Main Results:
- Only 8% of parents met with a genetic counselor; 23% underwent prenatal genetic testing.
- Maternal serum analyte screening and amniocentesis were common tests.
- Testing use correlated with advanced maternal age, not fertility treatments or conception time.
- 40% of those counseled declined testing, suggesting informed decision-making.
Conclusions:
- Multiple gestation pregnancies often do not access genetic counseling services.
- Genetic counseling can facilitate informed decisions regarding prenatal testing.
- Strategies are needed to improve access to and utilization of genetic counseling for these high-risk pregnancies.
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