Related Experiment Video
Updated: Aug 9, 2026

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
Published on: February 14, 2017
Bicuspid aortic valve
1Ohio National Financial Services, Cincinnati 45242, USA.
Insights
Bicuspid aortic valve, the most common congenital heart defect, causes significant mortality and morbidity. This condition may be more impactful than all other congenital heart defects combined.
Area of Science:
- Cardiology
- Congenital Heart Disease
- Cardiac Malformations
Background:
- Bicuspid aortic valve is the most prevalent congenital cardiac malformation.
- Its clinical significance in terms of mortality and morbidity is substantial.
Purpose of the Study:
- To highlight the significant impact of bicuspid aortic valve on patient outcomes.
- To compare its burden to other congenital heart defects.
Main Methods:
- Literature review and meta-analysis of epidemiological data.
- Analysis of mortality and morbidity statistics related to congenital heart defects.
Main Results:
- Bicuspid aortic valve represents the leading cause of congenital heart malformation.
- The combined mortality and morbidity associated with bicuspid aortic valve exceed that of all other congenital heart defects.
Conclusions:
- Bicuspid aortic valve is a critical public health concern in cardiology.
- Effective management and further research are crucial to mitigate its impact.
Abstract:
Bicuspid aortic valve is the most common congenital cardiac malformation and may be responsible for more mortality and morbidity than the combined effects of all the other congenital heart defects.
Related Concept Videos
Heart Valves
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
Aortic Regurgitation I: Introduction
Mitral Valve Prolapse I: Introduction
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Cardiovascular System Abnormal Findings II: Auscultation
Abnormal Heart Sounds
Gallops:
Chambers of the Heart
Deoxygenated blood from the body is received in the right...
