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Behcet's syndrome.

E Kovacova¹, J Salmas, E Stenova

¹1st Department of Internal Medicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia. E.Kovacova@zoznam.sk

Bratislavske Lekarske Listy

|April 29, 2006

Summary

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Behcet

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Area of Science:

Rheumatology
Internal Medicine
Immunology

Background:

Behcet's syndrome is a rare systemic vasculitis of unknown cause.
It typically presents with oral ulcers, genital ulcers, and eye inflammation.

Observation:

A 56-year-old man presented with fever, pulmonary infiltrates, mucosal defects, and kidney dysfunction.
Laboratory findings included Chlamydia pneumoniae infection, CIK positivity, and decreased C3 complement levels.

Findings:

Standard antibiotics and antifungals provided minimal improvement for pulmonary lesions.
High-dose prednisone followed by cyclophosphamide led to excellent resolution of all pathological findings.

Implications:

This case highlights an unusual presentation of Behcet's syndrome.

Aggressive immunosuppressive therapy, including corticosteroids and cyclophosphamide, can be effective in managing severe manifestations.