Related Experiment Video
Updated: Aug 9, 2026

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity
Revecca Theodori1, Anastasia Karioti, Ana Rancić
1Department of Pharmacognosy and Chemistry of Natural Products, School of Pharmacy, University of Athens, Panepistimiopolis, Zografou, GR-157 71 Athens, Greece.
Abstract:
Three linear sesquiterpene lactones, anthecotulide (1), hydroxyanthecotulide (2), and acetoxyanthecotulide (3), were isolated from the aerial parts of Anthemis auriculata. Five known flavonoids, taraxa-20(30)en-3beta-ol (4), and methyl vanillate (5) were also isolated. The structures and the relative configuration of the new compounds 2 and 3 were deduced by spectroscopic methods. The in vitro activity of compounds 1-5 against 10 bacterial species and one fungus was tested using the microdilution method.
Related Concept Videos
Clinical Significance of Antibiotic Resistance
Inhibitors of Gram-positive Cell Wall Synthesis
Surface Membrane Barriers
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
Production of Antibiotics
Antifungal Agents
