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Furoquinoline alkaloids from Melicope bonwickii (F.Muell.) T.Hartley
Ismiarni Komala1, Mawardi Rahmani, Mohd Aspollah Sukari
1Department of Chemistry, Universiti Putra Malaysia, 43400 UPM, Serdang, Malaysia.
Abstract:
Investigation on the leaves of Melicope bonwickii (F.Muell.) T.Hartley (Rutaceae) afforded a new 7-(2'-hydroxy-3'-chloroprenyloxy)-4-methoxyfuroquinoline (1) together with the known 7-(2',3'-epoxyprenyloxy)-4-methoxyfuroquinoline (2), evellerine (3) kokusaginine (4) and an amide aurantiamide acetate (5). Compounds 1 and 2 showed significant activity against cervical cell lines (Hela).
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