[Immunity and middle molecule levels in the blood of patients with brain tumors]

The immunity indicators (T general, T active and B lymphocytes, IgA, IgM and IgG, phagocytosis intensity and activity) and blood content of medium-size molecules (MSM) were studied in patients with brain tumors. Immunity disturbances were revealed in 96 +/- 4% of the patients whereas the increase of the content of MSM was detected in all the patients. The ratio of the absolute count of B lymphocytes to the count of T general lymphocytes (B/T) was offered for use. The magnitude of the ratio equal to 0.47-0.85 turned out characteristic of malignant tumors. The presence of MSM ranging within 0.390-0.480 units was common to the same tumors. The simultaneous demonstration of the characteristic magnitudes of the B/T and MSM in the patient permits one to reliably differentiate between malignant and benign brain tumors. The high magnitudes of MSM are prognostically unfavourable as regards the patients' survival after surgery.