Related Experiment Video
Updated: Aug 9, 2026

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability
Published on: April 22, 2016
Select the best: novel biocatalysts for industrial applications
Monika Konarzycka-Bessler1, Karl-Erich Jaeger
1Institute of Molecular Enzyme Technology, Heinrich-Heine University Duesseldorf, Research Centre Juelich, D-52428 Juelich, Germany.
Abstract:
The number of biocatalysts needed for biotechnological applications is increasing rapidly, necessitating the development of novel identification systems. To date, strategies based on high-throughput screening and selection are applied, with the latter enabling a desired phenotype to survive under appropriate conditions. The groups of Witholt and de Lorenzo have devised a novel selection system, comprising a transcriptional regulator that is activated upon binding to the product of a biocatalytic reaction, which paves the way for easier selection of many different biocatalysts.
Related Concept Videos
Bioreactor Controls-III
Bioreactor Design and Operational System
Production of Antibiotics
Catalytically Perfect Enzymes
Scale-Up Processes
Upstream Processing

