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Updated: Aug 9, 2026
Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
Evaluation of super-high-dose steroid therapy for sudden sensorineural hearing loss
Daisuke Aoki1, Hideki Takegoshi, Shigeru Kikuchi
1Department of Otorhinolaryngology, Saitama Medical Center, Saitama Medical School, Saitama, Japan.
Objective:
To determine the efficacy of a high-dose steroid regimen for patients with sudden sensorineural hearing loss (SSNHL) and to evaluate the relationship between outcome and initial steroid dose.
Study Design And Setting:
We conducted a retrospective study of 112 patients presenting to Saitama Medical Center. Patients received tapering courses of hydrocortisone (HC) with an initial dose of either 1200 mg or 600 mg.
Results:
More than 87% of patients had recovery of hearing. When hearing stabilized, there were no significant differences between the 1200 mg and 600 mg groups in terms of hearing outcome (P>0.05). However, at completion of treatment, the 1200 mg group exhibited significantly superior complete recovery rate and improvement rate (P<0.05).
Conclusion:
Application of our treatment protocol of a tapered course of 1200 mg HC significantly and rapidly improves recovery outcomes in patients of SSNHL.
Ebm Rating:
C-4.
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