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Published on: May 11, 2015
Pulmonary arterial pressure in children with croup syndrome
Bülent Oran1, Gülsün Ekici, Ismail Reisli
1Department of Pediatrics and Otorhinolaryngology, Meram Medical Faculty, Selçuk University, Konya, Turkey. pedkar@selcuk.edu.tr
Insights
Children with croup syndrome experience higher pulmonary arterial pressure, especially with severe symptoms. This elevated pressure is reversible with treatment, indicating the importance of monitoring during illness.
Area of Science:
- Pediatric Pulmonology
- Cardiology
- Critical Care Medicine
Background:
- Croup syndrome (laryngotracheitis) is a common cause of upper airway obstruction in children.
- Upper airway obstruction in children can lead to elevated pulmonary arterial pressure.
- The relationship between croup syndrome severity and pulmonary arterial pressure requires further investigation.
Purpose of the Study:
- To investigate the association between croup syndrome and pulmonary arterial pressure in pediatric patients.
- To compare pulmonary arterial pressure in children with croup syndrome versus healthy controls.
- To assess the impact of croup severity on pulmonary arterial pressure.
Main Methods:
- Echocardiography was used to measure pulmonary arterial pressure in 40 children with croup syndrome and 14 healthy controls.
- Patients were categorized into high croup score (>=6) and low croup score groups.
- High croup score patients received dexamethasone treatment, with serial measurements during therapy.
Main Results:
- Children with croup syndrome exhibited significantly higher pulmonary arterial pressures compared to healthy subjects at diagnosis.
- Patients with high croup scores had markedly elevated pulmonary arterial pressures versus the low croup score group (P < .05).
- Pulmonary arterial pressure normalized by the end of therapy in all treated patients.
Conclusions:
- Pulmonary arterial pressure increases in the acute phase of croup syndrome, correlating with disease severity.
- The elevation in pulmonary arterial pressure associated with croup syndrome is reversible.
- Doppler echocardiography is a valuable tool for monitoring pulmonary arterial pressure in children with croup syndrome.
Purpose:
Croup syndrome or laryngotracheitis is one of the frequent causes of transient upper airway obstruction by laryngeal and tracheal blockage in infants and children. Upper airway obstruction may lead to increased pulmonary arterial pressure in children. In this study, the relationship between croup syndrome and pulmonary arterial pressure was investigated.
Materials And Methods:
Forty children with croup syndrome and 14 healthy, age- and sex-matched control subjects were enrolled in this study. Of all patients, 12 with severe symptoms, such as dyspnea, cyanosis, hypoventilation, were accepted as "high croup score" (croup score >or=6). All patients with high croup score were treated with dexamethasone. We assessed pulmonary arterial pressure of patients during therapy using serial echocardiographic measurements.
Results:
Our results showed that children with croup syndrome have significantly higher pulmonary arterial pressures than healthy subjects at the time of diagnosis. Pressure values of patients with high croup score were found to be significantly higher when compared with those of the low -core group (P < .05). However, there was no difference between 2 groups at the end of therapy.
Conclusions:
It is suggested that pulmonary arterial pressure increased to different extents in the acute stage of illness and that the degree of increase was related to the severity of disease and average hospital stay. In addition, increased pulmonary arterial pressure due to croup syndrome is reversible. Furthermore, evaluation of children with croup syndrome by using Doppler echocardiography may be useful in the monitoring of pulmonary arterial pressure and in the follow-up of their therapy.
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