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Laryngeal manifestations and pediatric laryngopharyngeal reflux

Petros D Karkos1, Samuel C Leong, Maria T Apostolidou

  • 1Department of Otolaryngology, Alder Hey Children's Hospital, Liverpool, UK. pkarkos@aol.com

American Journal of Otolaryngology
|May 2, 2006
PubMed

Insights

Pediatric laryngopharyngeal reflux (PLPR) involves reflux affecting children's airways and throat. More research is needed to confirm its role in various pediatric respiratory and ear conditions.

Area of Science:

  • Otorhinolaryngology
  • Pediatric Gastroenterology
  • Pediatric Pulmonology

Background:

  • Pediatric laryngopharyngeal reflux (PLPR) presents as unusual throat and airway symptoms in children, linked to gastroesophageal reflux disease.
  • PLPR is considered a potential inflammatory factor in pediatric conditions like subglottic stenosis, asthma, croup, rhinosinusitis, and middle ear infections.

Purpose of the Study:

  • To review the literature on pediatric laryngopharyngeal reflux (PLPR).
  • To describe clinical manifestations of PLPR.
  • To highlight diagnostic and therapeutic challenges, particularly concerning laryngeal manifestations.

Main Methods:

  • Literature review of existing studies on pediatric laryngopharyngeal reflux.
  • Clinical case analysis and synthesis of reported manifestations.
  • Analysis of diagnostic controversies and treatment strategies.

Main Results:

  • Evidence linking reflux to pediatric laryngeal issues is primarily derived from animal or uncontrolled human studies.
  • PLPR is associated with a range of otorhinolaryngological and respiratory disorders in children.

Conclusions:

  • The current evidence base for PLPR's role in laryngeal problems requires strengthening.
  • Well-designed, controlled studies are essential for advancing the diagnosis and treatment of pediatric laryngopharyngeal reflux.

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