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Published on: March 14, 2019
[Selection of treatment modalities in children with chronic osteomyelitis]
Vuslat Sema Unal1, Avni Dayican, Murat Demirel
1Department of Orthopedics and Traumatology (1. Ortopedi ve Travmatoloji Kliniği), Ankara Numune Training and Research Hospital, Ankara, Turkey. vuslatsema@yahoo.com
Insights
Surgical debridement and antibiotics effectively treat pediatric chronic osteomyelitis in over half of cases. Bone reconstruction is vital for children with segmentary bone defects following initial treatment.
Area of Science:
- Orthopedic surgery
- Pediatric infectious diseases
Background:
- Chronic osteomyelitis in children presents complex treatment challenges.
- Trauma and fractures are common predisposing factors in pediatric cases.
Purpose of the Study:
- To evaluate clinical outcomes and treatment strategies for pediatric chronic osteomyelitis.
- To assess the effectiveness of surgical debridement and antibiotic therapy.
Main Methods:
- Retrospective analysis of 22 pediatric patients with chronic osteomyelitis.
- Involved surgical debridement, prolonged antibiotic courses, and immobilization (cast or external fixation).
- Bone reconstruction utilized for segmentary bone defects.
Main Results:
- Clinical improvement observed in 13 patients after debridement and antibiotics.
- Seven of nine patients with segmentary bone loss required bone reconstruction.
- Mean follow-up was 54 months.
Conclusions:
- Surgical debridement and antibiotic treatment yield satisfactory results for most pediatric chronic osteomyelitis cases.
- Bone reconstruction is essential for managing segmentary bone defects post-debridement.
Objectives:
We evaluated clinical and follow-up findings and treatment methods of pediatric patients with chronic osteomyelitis.
Methods:
The study included 22 children (14 boys, 8 girls; mean age 8+/-7 years) who were treated for chronic osteomyelitis. Infection sites were the femur, tibia, ulna, and radius in 11, 8, 1, and 2 patients, respectively. Sixteen patients had a history of trauma. Fourteen patients had fractures, nine of which were associated with segmentary bone defects. All the patients underwent at least one debridement and received antibiotic treatment for at least six weeks. When necessary, medications were modified according to the antibiogram results. Cast immobilization was applied, but external fixation was used when bone instability existed. The mean follow-up period was 54 months.
Results:
Clinical improvement was achieved in 13 patients following surgical debridement procedures, antibiotic treatment for six weeks, secondary grafting (5 patients), and cast immobilization. Of nine patients with segmentary bone losses, seven patients needed bone reconstruction procedures. Spontaneous shaft regeneration was observed in one patient with ulnar osteomyelitis.
Conclusion:
The results of surgical debridement and antibiotic treatment are satisfactory in more than half of the pediatric patients with chronic osteomyelitis. However, those developing segmentary bone defects after surgical debridement require bone reconstruction procedures.
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