Neuroimaging in children with first afebrile seizures: to order or not to order?

Fariba Khodapanahandeh1, Homayon Hadizadeh

  • 1Department of Pediatrics, * Iran University of Medical Sciences, Tehran, Iran. faribakoda@yahoo.com

Insights

Neuroimaging for children with new-onset afebrile seizures is often normal. Brain CT or MRI is recommended for those with focal seizures, abnormal findings, or under two years old.

Area of Science:

  • Pediatric Neurology
  • Emergency Medicine
  • Diagnostic Imaging

Background:

  • Seizures are a common pediatric emergency, accounting for 5% of emergency department visits.
  • The utility of emergent neuroimaging for first-time afebrile seizures in children lacks clear definition.

Purpose of the Study:

  • To evaluate the role and yield of emergent neuroimaging (CT scan or MRI) in children experiencing their first afebrile seizure.

Main Methods:

  • Retrospective review of medical charts for 125 children admitted with new-onset afebrile seizures.
  • Analysis of neuroimaging results (CT or MRI) performed within hours of emergency department arrival.

Main Results:

  • Neuroimaging was performed in 95% of eligible children.
  • The vast majority (90%) of neuroimaging results were normal.
  • Abnormal neuroimaging showed a significant association with focal seizures (P < 0.001) and younger age (< 2 years, P < 0.002).

Conclusions:

  • Emergent neuroimaging in children with first afebrile seizures has a low yield, with most results being normal.
  • Recommend CT scan or MRI for children with first afebrile seizures who exhibit focal seizures, abnormal neurological findings, or are under two years of age.

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