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A Periprosthetic Joint Candida albicans Infection Model in Mouse
Published on: February 2, 2024
[Pasteurella multocida and Candida albicans peritonitis]
1Servicio de Nefrología, Hospital Universitario La Paz, Madrid. hanko8@yahoo.com
Abstract:
Peritonitis is a well-known complication of peritoneal dialysis (PD) treatment. Repetitive episodes may induce an irreversible damage of the peritoneal membrane and are a frequent cause of PD drop-out. The great majority of the episodes are due to Staphylococci, Streptococci or gram- negative organisms. Unusual organisms have been reported, specially in immunosuppressed hosts. Few cases of Pasteurella Multocida (PM) have been described in PD patients. To our knowledge, we describe the first case preceding a Candida Albicans (CA) peritonitis. A review of the literature of PM peritonitis and the relation between these two microorganisms is discussed.
Insights
Peritonitis is a serious complication of peritoneal dialysis (PD). This study details a rare case of Pasteurella Multocida (PM) peritonitis followed by Candida Albicans (CA) peritonitis in a PD patient.
Area of Science:
- Nephrology
- Infectious Diseases
- Microbiology
Background:
- Peritonitis is a common complication of peritoneal dialysis (PD).
- Recurrent peritonitis can lead to irreversible peritoneal membrane damage and PD treatment cessation.
- Bacterial infections, primarily Staphylococci, Streptococci, and Gram-negative organisms, cause most PD peritonitis cases.
Observation:
- Unusual microorganisms can cause peritonitis, particularly in immunocompromised patients.
- Pasteurella Multocida (PM) peritonitis is rare in PD patients.
- This report describes the first known case of PM peritonitis preceding Candida Albicans (CA) peritonitis in a PD patient.
Findings:
- The study presents a unique case of sequential peritonitis involving Pasteurella Multocida followed by Candida Albicans.
- A literature review on PM peritonitis and the potential relationship between PM and CA infections in PD is discussed.
Implications:
- This case highlights the importance of considering unusual pathogens in PD peritonitis.
- Understanding the relationship between different microorganisms in sequential peritonitis is crucial for effective treatment strategies.
- Further research is needed to elucidate the interaction between Pasteurella Multocida and Candida Albicans in the context of PD-associated peritonitis.
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