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Updated: Aug 9, 2026
04:01
Transurethral Instillation Procedure in Adult Male Mouse
Published on: November 2, 2017
[Neurosyphilis and bladder dysfunction]
Antonio Jalón Monzón1, Alfonso San Martín Blanco, Jorge García Rodríguez
1Servicio de Urología, Hospital Universitario Central de Asturias, Oviedo, España. ajalonm@hotmail.com
Archivos Espanoles De Urologia
|May 3, 2006
Summary
Neurosyphilis, a late-stage syphilis complication, can cause bladder hyperreflexia. Early diagnosis through cerebrospinal fluid examination and urodynamic studies is crucial for managing neurogenic bladder.
Area of Science:
- Neurology
- Urology
- Infectious Diseases
Background:
- Syphilis is a systemic infection with potential late-stage neurological sequelae.
- Neurosyphilis can manifest with diverse clinical presentations, including neurological and psychiatric symptoms.
- Bladder dysfunction, specifically hyperreflexia, can arise from central nervous system involvement in late syphilis.
Observation:
- A 51-year-old male presented with voiding disorders.
- The patient had a confirmed diagnosis of neurosyphilis.
- Urodynamic studies revealed detrusor hyperactivity indicative of a neurogenic etiology.
Findings:
- Neurosyphilis was identified as the cause of neurogenic bladder hyperreflexia in this case.
- Cerebrospinal fluid examination confirmed the etiological diagnosis of neurosyphilis.
- Urodynamic studies were essential in diagnosing the bladder dysfunction.
Implications:
- Neurosyphilis should be considered in the differential diagnosis of neurogenic bladder, especially in patients with neurological or psychiatric symptoms.
- Prompt etiological diagnosis via cerebrospinal fluid analysis is critical.
- Urodynamic assessment is vital for characterizing bladder dysfunction in suspected neurosyphilis cases.
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