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The paediatric burden of rotavirus disease in Europe

    Epidemiology and Infection
    |May 3, 2006
    PubMed

    Insights

    Rotavirus disease causes significant hospitalizations in European children under five. This review highlights the substantial burden, informing the need for rotavirus vaccines.

    Area of Science:

    • Pediatrics
    • Infectious Diseases
    • Public Health

    Background:

    • Rotaviruses are a leading cause of acute gastroenteritis hospitalizations in developed nations.
    • The burden of rotavirus disease in children under five years old in Europe requires detailed examination.

    Purpose of the Study:

    • To review and quantify the burden of rotavirus disease in children under five years old within the European Union (EU-25).
    • To provide data supporting the introduction of rotavirus vaccines in EU-25 countries.

    Main Methods:

    • This study is a review of existing data on rotavirus disease burden.
    • Estimates of annual hospitalizations, incidence rates, and costs were compiled for the EU-25 population under five.

    Main Results:

    • An estimated 72,000-77,000 annual hospitalizations for community-acquired rotavirus disease occur in EU-25 children under five.
    • Median hospitalization cost is Euro 1417 per case, with incidence rates varying from 0.3 to 11.9 per 1000 children.
    • Hospital-acquired rotavirus disease accounts for a median of 21% of all rotavirus hospitalizations.

    Conclusions:

    • Rotavirus disease poses a significant health and economic burden on young children in Europe.
    • Limited data exist on non-hospitalized cases, medical visits, and deaths, hindering a full impact assessment.
    • Further epidemiological studies are crucial for evaluating the effectiveness of rotavirus vaccination programs in Europe.

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