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Autosomal STR data on the enigmatic Andaman Islanders.
K Thangaraj1, G Chaubey, A G Reddy
1Centre for Cellular and Molecular biology, Hyderabad 500 007, India.
Forensic Science International
|May 3, 2006
Summary
Genetic analysis of Andaman islanders using nine autosomal STR loci reveals high and consistent genetic diversity across Great Andamanese, Onge, and Nicobarese populations. This indicates significant genetic variation within these unique groups.
Area of Science:
- Population Genetics
- Forensic Science
- Human Evolutionary Studies
Background:
- The Andaman Islands harbor unique indigenous populations with limited genetic studies.
- Understanding the genetic landscape of these groups is crucial for anthropological and forensic applications.
Purpose of the Study:
- To analyze genetic diversity in Andaman islanders using autosomal Short Tandem Repeat (STR) loci.
- To compare genetic profiles with Indian and Southeast Asian populations.
Main Methods:
- Analysis of nine autosomal STR loci (D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820) in 97 individuals.
- Statistical analyses including Heterozygosity (H), Power of Discrimination (PD), Probability of Exclusion (PE), Typical Paternity Index (TPI), Polymorphism Information Content (PIC), AMOVA, and Arlequin analysis.
- Comparative analysis with existing population genetic data from India and Southeast Asia.
Main Results:
- High average heterozygosity was observed across all analyzed Andamanese populations (Great Andamanese, Onge, Nicobarese).
- Key forensic genetic parameters such as Power of Discrimination (PD), Probability of Exclusion (PE), Typical Paternity Index (TPI), and Polymorphism Information Content (PIC) were consistently high and similar among the groups.
- Genetic data showed comparable diversity metrics within the Andamanese populations and in relation to broader regional groups.
Conclusions:
- The analyzed Andamanese populations exhibit substantial and uniform genetic diversity.
- The findings support the utility of these STR loci for forensic identification and population genetic studies within the Andamanese and related populations.