Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Interactions between bacteria and eukaryotes via small molecules.

Robert Dudler1, Leo Eberl

  • 1Department of Microbiology, Institute of Plant Biology, University of Zürich, Switzerland.

Current Opinion in Biotechnology
|May 3, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Host Factor Induced Bacterial Extracellular Vesicles Promote Horizontal Gene Transfer in Vibrio cholerae.

Journal of extracellular vesicles·2026
Same author

Extensive spontaneous genome reduction in Paraburkholderia sabiae.

Scientific reports·2026
Same author

Identifying phenotypic and genetic traits for assessing pathogenic potential and biocontrol capacity in Burkholderia sensu lato strains.

The ISME journal·2026
Same author

High-resolution visualization of biofilm matrix development in space and time using fluorescent stains for cellulose.

NPJ biofilms and microbiomes·2026
Same author

Versatile roles of rubredoxin reductase of Pseudomonas aeruginosa TBCF10839 in virulence and stress protection.

PLoS pathogens·2025
Same author

Enrichment of human IgA-coated bacterial vesicles in ulcerative colitis as a driver of inflammation.

Nature communications·2025

Interactions between eukaryotes and bacteria involve small molecules, often from symbiotic bacteria. Research confirms bacterial signaling is crucial for these host interactions, opening doors for biotechnology and therapeutics.

Area of Science:

  • Microbiology
  • Biotechnology
  • Natural Product Chemistry

Background:

  • Eukaryote-bacteria interactions are vital for biotechnology and therapeutics.
  • Small molecules mediate many of these interactions, driving research in natural product chemistry.
  • Recent findings highlight symbiotic bacteria as key producers of bioactive compounds.

Purpose of the Study:

  • To explore the role of small molecules in eukaryote-bacteria interactions.
  • To investigate the origin of pharmacologically active natural products.
  • To confirm the significance of bacterial cell-to-cell communication.

Main Methods:

  • Isolation and characterization of small molecules from diverse natural sources.
  • Analysis of secondary metabolite production in symbiotic bacteria.

Related Experiment Videos

  • Investigation of bacterial signaling pathways in host interactions.
  • Main Results:

    • Numerous small molecules with diverse activities were isolated.
    • Evidence suggests symbiotic bacteria, not hosts, often produce key metabolites.
    • Bacterial cell-to-cell signaling plays a confirmed role in host interactions.

    Conclusions:

    • Symbiotic bacteria are significant sources of bioactive small molecules.
    • Bacterial signaling is essential for understanding and manipulating eukaryote-bacteria interactions.
    • This knowledge can advance therapeutic and biotechnological applications.