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Identification of novel genes with prognostic value in childhood leukemia using cDNA microarray and quantitative

Hiroyoshi Hattori1, Akinobu Matsuzaki, Aiko Suminoe

  • 1Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. hhattori@pediatr.med.kyushu-u.ac.jp

Pediatric Hematology and Oncology
|May 3, 2006
PubMed

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...