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Updated: Aug 9, 2026

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection
Published on: July 21, 2013
Moyamoya syndrome with primary antiphospholipid syndrome
Mohammed Ali Shuja-Ud-Din1, Shefeek Abubacker Ahamed, Ghassan Baidas
1Department of Medicine, Al-Sabah Hospital, Kuwait. shujadr@hotmail.com
Objectives:
To report a rare case of moyamoya syndrome with primary antiphospholipid syndrome (APS).
Clinical Presentation And Intervention:
A 41-year-old woman was admitted with sudden onset of left-sided hemiparesis. Magnetic resonance imaging and magnetic resonance angiography of the brain showed characteristic features of moyamoya vessels. Laboratory investigations revealed raised levels of anticardiolipin antibody. She made a complete and uneventful recovery with aspirin and intensive physiotherapy over a period of 2 weeks.
Conclusion:
The association of APS and moyamoya disease may present a dilemma in management. While APS is often considered to be an indication for giving anticoagulation, a trial of antiplatelet agents is preferable to anticoagulation because of the risk of bleeding from the fragile moyamoya vessels.
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