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Related Experiment Videos

An effervescent reaction micropump for portable microfluidic systems.

Brian T Good1, Christopher N Bowman, Robert H Davis

  • 1Department of Chemical and Biological Engineering, ECCH 111, UCB 424, University of Colorado, Boulder, CO 80309-0424, USA.

Lab on a Chip
|May 3, 2006
PubMed
Summary

This study presents a novel effervescent reaction pump for portable microfluidic devices. The water-activated pump offers controllable fluid transport by adjusting reaction parameters for precise carbon dioxide generation.

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Area of Science:

  • Microfluidics
  • Chemical Engineering
  • Materials Science

Background:

  • Microfluidic devices require efficient and controllable fluid pumping mechanisms.
  • Existing micropumps often face limitations in portability, cost, or ease of use.
  • Effervescent reactions offer a potential low-cost, on-demand fluid propulsion method.

Purpose of the Study:

  • To develop and characterize a novel water-activated effervescent reaction pump for portable microfluidic applications.
  • To model and control carbon dioxide gas generation for precise fluid transport.
  • To integrate and test the effervescent pump within a microfluidic device using elastomeric polymers.

Main Methods:

  • Modeling the reaction between sodium bicarbonate and organic acids (tartaric and benzoic acid) to control carbon dioxide generation.

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  • Utilizing elastomeric polymers for photopolymerizable septa and removable lids in microfluidic device fabrication.
  • Integrating and testing the effervescent reaction pump in a microfluidic device.

    • Main Results:

    • Achieved controllable fluid pumping with flow rates ranging from 0.01 to 70 microL/s.
    • Demonstrated that flow rate can be tuned by adjusting reactant particle size, amount, and organic acid type.
    • Observed distinct gas generation profiles: rapid but decaying with tartaric acid, slower but sustained with benzoic acid.

    Conclusions:

    • The developed effervescent reaction pump is a viable, water-activated solution for controllable fluid transport in portable microfluidics.
    • The pump's performance is tunable by manipulating key reaction parameters.
    • Elastomeric polymers facilitate the integration and accessibility of gas-tight microfluidic devices.